非酒精性脂肪性肝病相关肝纤维化研究进展
Advances in the Study of Fibrosis Associated with Nonalcoholic Fatty Liver Disease

随着人们生活水平的提高，在全球范围内，非酒精性脂肪性肝病的发病率呈逐年上升趋势，而非酒精性脂肪性肝炎是疾病进展的主要驱动力，是肝脏相关病变结果的重要预后因素。为此早期诊断非酒精性脂肪性肝炎和准确评估肝纤维化的严重程度对于治疗策略、治疗反应、判断预后是至关重要的。然而，目前对于非酒精性脂肪性肝炎的无创诊断方法仍是临床医师面临的一大困境。本文将根据最新研究进展，对现有的无创诊断方法进行阐述。
With the improvement of people’s living standard, the incidence of non-alcoholic fatty liver disease is on the rise year by year globally. Non-alcoholic steatohepatitis is the main driving force of the disease progression and an important prognostic factor for the outcome of liver-related lesions. For this reason, early diagnosis of nonalcoholic steatohepatitis and accurate assessment of the severity of liver fibrosis are crucial for treatment strategy, treatment response, and prognosis. However, noninvasive diagnostic methods for nonalcoholic steatohepatitis remain a major dilemma for clinicians. In this paper, based on the latest research progress, the existing non-invasive diagnostic methods are described.