白细胞介素-10在肝脏疾病中的作用
Role of the Cytokine Interleukin-10 in Liver Disease

DOI: 10.12677/BP.2020.101001, PP. 1-7

Keywords: 白细胞介素-10，抗炎，肝脏疾病，治疗潜力
Interleukin (IL)-10, Anti-Inflammatory, Liver Disease, Therapeutic Potential

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Abstract:

白细胞介素(IL)-10是机体内一种关键的抗炎介质，确保宿主免受病原体等造成的过度免疫反应的影响，同时在伤口愈合、自身免疫、癌症以及维持机体稳态等方面发挥重要作用。近年来，大量研究表明了IL-10在肝脏疾病方面的关键作用，如肝炎、肝纤维化、肝癌以及肝衰竭等。本文就目前IL-10在肝脏疾病方面取得的突破成就进行综述，并进一步讨论IL-10在不同疾病背景下的治疗潜力。
Interleukin (IL)-10 is a key anti-inflammatory mediator in the body, ensuring that the host is protected from over-immunity caused by pathogens, etc. It also plays an important role in wound healing, autoimmunity, cancer and the maintenance of homeostasis. In recent years, numerous studies have demonstrated the critical role of IL-10 in liver diseases such as hepatitis, fibrosis, liver cancer, liver failures, etc. This article provides an overview of the current breakthrough achievements of IL-10 in liver disease and further discusses the role of IL-10 in different therapeutic potential in the disease context.

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