尿酸和疾病的关系研究进展
Research Progress of the Relationship between Uric Acid and Disease

DOI: 10.12677/BP.2020.103004, PP. 20-26

Keywords: 尿酸，疾病，综述
Uric Acid, Disease, Review

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Abstract:

尿酸是嘌呤代谢的终产物，血浓度超过一定阈值会导致躯体疼痛、功能受损。目前认为高尿酸血症与心血管疾病、代谢综合征、卒中、肾脏疾病等密切相关，然而尿酸与各类疾病的关系、尿酸是否是这些疾病的独立危险因素的结论尚未达成共识。本文就尿酸与心血管疾病、肾脏疾病、癌症、糖尿病、神经系统疾病的关系进行综述。
Uric acid is the end product of purine metabolism. It will cause physical pain and impaired function when the blood concentration exceeds a certain threshold. It is acknowledged that hyperuricemia is related to cardiovascular disease, metabolic syndrome, stroke and kidney disease. However, there is no consensus on the relationship between uric acid and different diseases and whether uric acid is an independent risk factor of these diseases. This article reviews the relationship between uric acid and cardiovascular disease, kidney disease, cancer, diabetes, and nervous system disease.

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