Altered velocity gradient in lower limb chronic venous disease

In physiology, velocity of the deep venous compartment is higher than the one in the saphenous compartment which is higher than the one in the tributaries. Considering that velocity variation is associated with changes in the pressure gradient, aim of the present study is to assess changes in venous kinetics in case of superficial chronic venous disease, so to provide further clues in venous drainage direction determination. Venous ultrasound scanning was performed on 40 lower limbs of 28 chronic venous disease patients (C2-6Ep,As,Pr). Velocities were measured in three different venous segments: great saphenous vein at 2？cm above the origin of the incompetent tributary (Group-A). great saphenous vein at 2？cm below the origin of tributary (Group-B). tributary at 2？cm from its origin from the great saphenous vein (Group-C.) Diastolic time average velocity was higher in group-C (？21.3？±？8.5？cm/s) than in group-A (？15.7？±？5.2？cm/s; p？=？.0001) and group-B (？11.1？±？2.9？cm/s; p？=？.0001), thus indicating an inversion of the physiological velocity gradient in chronic venous disease patients. Chronic venous disease presents a subverted velocity gradient. These data introduce objective hemodynamics data, paving the way for further investigation in venous drainage direction determination