Antimicrobial stewardship through telemedicine and its impact on multi

Telemedicine technologies are increasingly being incorporated into infectious disease practice. We aimed to demonstrate the impact of antimicrobial stewardship through telemedicine on bacterial resistance rates. We conducted a quasi-experimental study in a 220-bed hospital in southern Brazil. An antimicrobial stewardship program incorporating the use of telemedicine was implemented. Resistance and antimicrobial consumption rates were determined and analysed using a segmented regression model. After the intervention, the rate of appropriate antimicrobial prescription increased from 51.4% at baseline to 81.4%. Significant reductions in the consumption of fluoroquinolones (level change, β？=？？0.80; P？<？0.01; trend change, β？=？？0.01; P？=？0.98), first-generation cephalosporins (level change, β？=？？0.91; P？<？0.01; trend change, β？=？+0.01; P？=？0.96), vancomycin (level change, β？=？？0.47; P？=？0.04; trend change, β？=？+0.17; P？=？0.66) and polymyxins (level change, β？=？？0.15; P？=？0.56; trend change, β？=？？1.75; P？<？0.01) were identified. There was an increase in the consumption of amoxicillin？+？clavulanate (level change, β？=？+0.84; P？<？0.01; trend change, β？=？+0.14; P？=？0.41) and cefuroxime (level change, β？=？+0.21; P？=？0.17; trend change, β？=？+0.66; P？=？0.02). A significant decrease in the rate of carbapenem-resistant Acinetobacter spp. isolation (level change, β？=？+0.66; P？=？0.01; trend change, β？=？？1.26; P？<？0.01) was observed. Telemedicine, which provides a tool for decision support and immediate access to experienced specialists, can promote better antibiotic selection and reductions in bacterial resistance