Diagnostic challenges and therapeutic possibilities in spontaneous intracranial hypotension

Spontaneous intracranial hypotension (SIH) has gained more attention in the eyes of clinicians in the past years and is now recognized as an important cause of headaches. While usually self-limiting and benign, some patients suffer from debilitating symptoms that interfere significantly with their social and professional life. Thus, recognition and adequate treatment of SIH is of paramount importance. Recent refinements in imaging techniques combined with modern microneurosurgical techniques offer many diagnostic and therapeutic possibilities today. The aim of this review is to give the reader an updated review on the state-of-the art in the challenging diagnosis and treatment of SIH as well as an insight into recent developments of pathophysiological concepts and affiliations with other enigmatic diseases