Reproducibility and non-redundancy of radiomic features extracted from arterial phase CT scans in hepatocellular carcinoma patients: impact of tumor segmentation variability

Hepatocellular carcinoma (HCC) is one of the most prevalent cancers in the world and has a poor prognosis (1). It is the leading cause of cancer death in men before the age of 60, followed by lung and stomach cancer, which are the dominant types of cancer with respect to the number of cases and deaths between the ages of 60 to 74 years in China (2)