Quantitative features of dual-energy spectral computed tomography for solid lung adenocarcinoma with EGFR and KRAS mutations, and ALK rearrangement: a preliminary study

As the main histological subtype of pulmonary cancer, adenocarcinoma is considered a heterogeneous malignancy based on molecular features (1,2). A recent study demonstrated that patients with lung adenocarcinoma can be treated by novel therapeutics targeting signaling pathways (3). Moreover, precise characterization of lung adenocarcinoma at the genetic level is a fundamental requirement for personalized therapy targeting the involved driver oncogenes