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-  2019 

In-depth mining of clinical data: the construction of clinical prediction model with R

DOI: 10.21037/atm.2019.08.63

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Abstract:

For a doctor, if there is a certain “specific function” to predict whether a patient will have some unknown outcome, then many medical practice modes or clinical decisions will change. Such demand is so strong that almost every day we will hear such a sigh “If I could know in advance, I would certainly not do this!”. For example, if we can predict that a patient with malignant tumor is resistant to a certain chemotherapy drug, then we will not choose to give the patient the drug; if we can predict that a patient may have major bleeding during surgery, then we will be careful and prepare sufficient blood products for the patient during the operation; if we can predict that a patient with hyperlipidemia will not benefit from some lipid-lowering drug, then we can avoid many meaningless medical interventions

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