Rapid and sensitive detection of Shigella flexneri using fluorescent microspheres as label for immunochromatographic test strip

Shigella can cause an acute bloody diarrhea in humans which is becoming an increasing public health burden due to development of multiple antimicrobial resistance frequently resulting in treatment failure (1,2). It has been estimated that 165 million cases of shigellosis occur annually worldwide, resulting in 1.1 million deaths (3-5)