CMTTdb: the cancer molecular targeted therapy database

Cancer has emerged as one of the most prominent causes of death worldwide. According to the Global Cancer Statistics, cancer incidence and mortality rates have been continuing to rise worldwide in the past decade (1). It represents an enormous economic and social burden to society. Until now, the surgical resection and/or traditional chemotherapy by using cytotoxic drugs is still the major choice for cancer treatment (2). The cytotoxic drugs block carcinogenesis and tumor growth by interfering with rapidly dividing cells (3). Most of the cytotoxic drugs, however, present limited therapy efficiency and severe side effects in clinical use. Thus, it is critical to develop more effective and less harmful treatment methods which lead to better patient care