Boosting autophagy in the diabetic heart: a translational perspective

Despite the great advances in both primary and secondary prevention, cardiovascular diseases still represent the main cause of death in Western countries (1). Metabolic derangements such as diabetes, obesity, and dyslipidemia are critical factors that directly promote the development of coronary artery disease, stroke, and heart failure and dramatically affect the prognosis of subjects affected by cardiovascular diseases (1)