Prognostic impact of tumour-associated B cells and plasma cells in oesophageal and gastric adenocarcinoma

Oesophageal cancer is now the eighth most common type of cancer and sixth most common cause of cancer related deaths, with an estimated number of 400,000 deaths worldwide annually (1). In the westernized world there has been a steady increase in adenocarcinoma of the esophagus, now surpassing squamous cell carcinoma (1). Gastric cancer, while overall declining in the west, is still the fifth most prevalent cancer worldwide, and the third when it comes to cancer related deaths, with an estimated number of 723,000 deaths annually (1)