Overexpression of cancer cell-derived immunoglobulin G correlates with poor prognosis in gastric cancer patients

Gastric cancer (GC) is the fourth most prevalent malignant tumor worldwide and the leading cause of cancer-related death in China (1,2). Although the overall prognosis of GC has gradually improved over the past decades, the survival of GC patients is still dismal with the advanced stage or inoperable tumor at the time of diagnosis (3-5). In this context, it is necessary to develop new biomarkers with the potential to estimate the efficacy of therapeutic strategies and prognosis