Prognosis after wedge resection in patients with 8 th edition TNM stage IA1 and IA2 non-small cell lung cancer

The standard treatment of stage I non-small cell lung cancer (NSCLC) has been anatomical lobectomy with mediastinal lymph node dissection (1). However, for smaller (≤2 cm) tumors, the prognosis after sublobar resection (segmentectomy or wedge resection) may be comparable to that of lobectomy, although the results are not conclusive (2,3). At the time of this writing, two ongoing randomized trials (CALGB 140503 and JCOG 0802) were in progress to investigate the hypothesis that sublobar resection is comparable to lobectomy for small-sized (≤2 cm) NSCLC (4,5)