Microarray screening for key genes and prognosis factors in interferon regulatory factor 1-silenced ovarian cancer SKOV-3 cells

Ovarian cancer is a gynecological neoplastic disease and the fifth most common cause of cancer mortality in women (1). Survival of patients with ovarian cancer is reported to be highly related to the stage of cancer: 5-year survival rate for patients with early-stage cancer is 80–90%, whereas that for patients with advanced-stage disease is merely 25% (2)