A rare unilateral giant fibroadenoma of the breast during pregnancy and lactation

Giant fibroadenoma (GFA) accounts for 2% to 10% of all fibroadenomas in breasts. GFA is referred to when a tumor reaches a size larger than 5 cm in diameter and/or weighs more than 500 g. GFA is an uncommon variant of fibroadenoma and the most common cause of unilateral macromastia in adolescents (1). Pregnancy is associated with profound changes in maternal breasts. A hormonal milieu of pregnancy induces lobular and alveolar proliferative changes. During pregnancy, in response to hormonal stimulus, fibroadenomas often increase in size and occasionally become infarcted, causing a significant increase in size and pain, which may often be confused with cancer. Physiologic changes associated with pregnancy make it difficult to detect small lesions (2). However, when GFA causes significant deformity and suspicion of malignancy, surgical excision is required (3). We presented a case of GFA in the left breast during pregnancy and lactation