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-  2018 

miRNAs as biomarkers and for the early detection of non-small cell lung cancer (NSCLC)

DOI: 10.21037/jtd.2018.05.32

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Abstract:

Lung cancer is the most frequently diagnosed cancer and the most common cause of cancer death worldwide, accounting for an estimated 1.8 million new cases and 1.6 million deaths in 2012 (1). Approximately 85% of lung cancers are classified as non-small cell lung cancer (NSCLC), a less aggressive form of tumor than small cell lung cancer (the remaining 15% of all lung cancers). According to Surveillance, Epidemiology, and End Results (SEER) Cancer Statistics Review, the 5-year survival rate of NSCLC remains as low as 23.6% because only 19% of cases are diagnosed at localized stages when the disease is highly curable with a 59.5% 5-year survival rate (2)

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