Management of drug-resistant tuberculosis in special sub-populations including those with HIV co-infection, pregnancy, diabetes, organ-specific dysfunction, and in the critically ill

Despite a slight decline in the global tuberculosis incidence over the last 13 years, there remains a substantial burden of disease with an estimated 10.4 million incident cases in 2015 (1). According to World Health Organization (WHO) estimates, ~1.8 million people died from TB in the same year making tuberculosis the world’s leading infectious cause of death (2)