Clinicopathological characteristics of solitary cavitary lung cancer: a case-control study

Lung cancer is the most common malignant tumor in China and the world, and identified as the main cause of cancer-related death (1,2). It has been reported that r cavitary lesions was presented in 2% to 25% of lung cancer (3), with larger tumor tissue size, more squamous cell histology and poor prognosis (4-6). In recent years, with the continuous development of high-resolution computed tomography (HRCT) and other radiological technologies, more and more cavitary lung nodules smaller than 3 cm were found. At present, clinicopathological characteristics of cavitary lung cancer are mainly about squamous cell carcinoma based on previous published studies. However, cavitary adenocarcinoma becomes more dominantly with the increasing incidence of adenocarcinoma. As a result, the composition and structure of cavitary lung cancer have been significantly changed as adenocarcinoma presented more, raising the requirement of reevaluation of clinicopathological features cavitary lesions