A comparison study of post-operative infection analysis of cold-knife conization and loop electrosurgical excision procedure for cervical high-grade squamous intraepithelial lesion

High-grade squamous intraepithelial lesion (HSIL) is a premalignant condition of the cervical cancer. Patients suffering from HSIL can be diagnosed by a three-step screening. To prevent the cancer foundation, surgical excision is usually carried out especially in high-grade lesions (1). This way was also prude to be effective. As a traditional procedure for HSIL, cold-knife conization (CKC) is typically performed in hospitals. While in 1989, Prendiville (2) adapted a new excision procedure—loop electrosurgical excision procedure (LEEP) to do the treatment. Wright and Lindeque described LEEP was an effective method for evaluation and treatment of HSIL (3,4). These recommended treatments are two main methods of excision for high grade lesion with their respective advantages and disadvantages (4,5). Many researchers (6-9) compared LEEP with CKC in HSIL focusing on the recurrence rate, positive margin rate, residual disease rate, secondary hemorrhage or cervical stenosis. Their data suggested that LEEP is as effective as CKC in HSIL treatment according to the recurrence rate, positive margin rate, residual disease rate, secondary hemorrhage, and cervical stenosis (10,11)