Expression of neuritin in human lung squamous cell carcinoma

Neuritin, also known as candidate plasticity-related gene 15, is a novel neurotrophin discovered by Nedivi et al. (1). It is an activity-induced glycosylphosphatidylinositol-anchored axonal protein, mainly expressed in the brain (2,3). Neuritin has been proven to have a profound effect in the nervous system by promoting neurite outgrowth and dendritic growth, regulating synaptic plasticity, promoting synaptic maturation and neuronal migration, regenerating peripheral nerves and spinal axons, and regulating proliferative neuron apoptosis (3-13). However, information on the functions of neuritin in other organs is scarce