Current perspectives for the size measurement of screeningdetected lung nodules

Lung cancer is the leading cause of cancer-related mortality worldwide. National Lung Screening Trial (NLST) demonstrated reduced lung cancer mortality of 20% for whom underwent annual low-dose CT screening (1). For the screening-detected nodules, size measurement is mandatory as the nodule size is directly proportional to the lung cancer risk (2). For the size estimation, uni-dimensional or bi-dimensional diameter measurement have been the standard in practice. Diameter measurement is easy, practical, and has been adopted as the standard method in the clinical practice guidelines for the management of lung nodules (3-6)