A case report of giant esophageal neurofibroma

Benign esophageal tumors are rare in comparison to esophageal malignancies. Attah found only 26 cases of benign esophageal tumors in a 30-year review of 15,454 autopsies, with a prevalence of 0.17% (1). Leiomyoma is the most common benign esophageal tumor in both surgical and autopsy series, while hemangioma, hamartoma and neurofibroma are rarely seen (2). Neurofibromas are generally associated with hereditary diseases and usually have a manifestation of von Recklinghausen disease (VRD) (3). Sex hormones play a potential role in etiology, and the male preponderance was found (4). About half of the patients with benign esophageal tumor are asymptomatic. Smaller lesions are detected accidentally, while the larger ones can cause compressive symptoms. Variety of surgical treatments has been reported to remove these lesions (5-7). Successful surgical resection of the giant neurofibroma forms the basis of present report