Surgical and oncological outcomes after laparoscopic vs. open major hepatectomy for hepatocellular carcinoma: a systematic review and meta-analysis

Hepatocellular carcinoma (HCC) is the most frequent type of primary liver cancer, the sixth most commonly diagnosed cancer, and fourth dominating cause of cancer deaths worldwide according to 2018 global cancer statistics (1). Currently, the management of HCC depends mainly on multidisciplinary comprehensive treatment, of which surgical resection remains the prime therapeutic method for patients without distant metastasis (2)