Soft Tissue Sarcomas : A Clinicopathological Study And Review

AIM: We reviewed cases of soft-tissue sarcoma to gain insight into the presentation, treatments and outcomes for this rare disease and to determine various factors associated with outcomes. METHODS:This is a retrospective study of histologically confirmed cases of soft tissue sarcoma seen at RIMS Ranchi over a period of 2 years between Jan 2012 and Dec. 2014. Data were retrieved from patientsa？？ files and analyzed using SPSS computer software version 16.0 RESULTS: A total of 30 cases were studied. Male to female ratio was 4:1. Mean age of presentation was 46.5 ？± 9.2 years. Most common site was lower limb (46.7%) followed by upper limb(16.7%). The vast majority of patients (56.7%) presented with large tumors of a？￥10 cm in diameter. Lymph node metastasis at the time of diagnosis was recorded in 23.3% of cases and distant metastasis was present in 30% cases. Liposarcoma (30.0%) was the most common histopathological type followed by fibrosarcoma (23.3%). Surgical excision was the most common surgical procedure performed in 76.7% of cases. Surgical site infection was the most common complication in 43.0% of patients. Local recurrence was noted in 16.0% of cases. Mortality rate was 43.3%. CONCLUSION: In conclusion, soft tissue sarcomas are aggressive tumor and has a high propensity for metastasis. Early diagnosis and complete excision of a small primary tumor is important in the treatment of soft tissue sarcomas