Objective: To determine the prevalence of human metapneumovirus (hMPV) among children with acute respiratory tract infection and the correlation between (hMPV) and age group. Methods: This prospective, descriptive cross-sectional hospital-based study is carried out from January to May 2019 among children from under five years old who were admitted to El-Obeid pediatric teaching Hospital, North kordofan, Sudan with acute respiratory tract infection. Results: Fifty hospitalized children with acute respiratory tract infection were enrolled in the study. Two of these (4%) were tested positive for (hMPV) in the age group (7 months - 2 years) old. Moreover, the study showed no significant correlation between infection with (hMPV) and age.
References
[1]
Greenberg, S.B. (2002) Respiratory Viral Infections in Adults. Current Opinion in Pulmonary Medicine, 8, 201-208.
https://doi.org/10.1097/00063198-200205000-00009
[2]
Hall, C.B. (2001) Respiratory Syncytial Virus and Parainfluenza Virus. The New England Journal of Medicine, 344, 1917-1928.
https://doi.org/10.1056/NEJM200106213442507
[3]
Owor, B.E., Masankwa, G.N., Mwango, L.C., Njeru, R.W., Agoti, C.N. and Nokes, D.J. (2016) Human Metapneumovirus Epidemiological and Evolutionary Patterns in Coastal Kenya. 2007-11. BMC Infectious Diseases, 16, Article No. 301.
https://doi.org/10.1186/s12879-016-1605-0
[4]
Steffen, C., Debellut, F., Gessner, B.D., Kasolo, F.C., Yahaya, A.A., Ayebazibwe, N., et al. (2012) Improving Influenza Surveillance in Sub-Saharan Africa. Bull World Health Organ, 90, 301-305. https://doi.org/10.2471/BLT.11.098244
[5]
Steffen, C., Diop, O.M., Gessner, B.D., Hacen, M.M., Hassar, M., Katz, M.A., et al. (2011) Afriflu-International Conference on Influenza Disease Burden in Africa, 1-2 June 2010, Marrakech, Morocco. Vaccine, 29, 363-369.
https://doi.org/10.1016/j.vaccine.2010.11.029
[6]
Attar, O.A. and Enan, K.A. (2017) Detection of Human Metapneumovirus in Hospitalized Children with Acute Respiratory Tract Infections in Khartoum State (Sudan). African Journal of Medical Sciences, 2.
[7]
Mona, S., Mohamed, E., Reiche, J., Jacobsen, S., Thabit, A.G., Badary, M.S., et al. (2014) Molecular Analysis of Human Metapneumovirus Detected in Patients with Lower Respiratory Tract Infection in Upper Egypt. International Journal of Microbiology, 2014, Article ID: 290793.
[8]
Al-Turab, M., Chehadeh, W., Al-Mulla, F. and Al-Nakib, W. (2011) Human Metapneumovirus in Patients with Respiratory Tract Infection in Kuwait. Journal of Medical Virology, 83, 1811-1817. https://doi.org/10.1002/jmv.22193
[9]
Ramirez, B.J., Dominguez, P., Benito, G.R., Rico, M.J., Castellanos, J. and Martinez, A.P. (2014) Human Respiratory Syncytial Virus and Metapneumovirus in Patients with Acute Respiratory Infection in Colombia, 2000-2011. Revista Panamericana de Salud Pública, 36, 101-109.
[10]
Alsuheel, A.M., Ali, A.S., Al-Hakami, A.M., Shati, A.A., Chandramoorthy, H.C.and Al-Qahtani, S.M. (2019) Human Metapneumovirus in Pediatric Patients with Acute Respiratory Tract Infections in the Aseer Region of Saudi Arabia. Saudi Journal of Medicine and Medical Sciences, 7, 80-85.
https://doi.org/10.4103/sjmms.sjmms_72_18
[11]
Zhang, L., Liu, W., Liu, D., et al. (2018) Epidemiological and Clinical Features of Human Metapneumovirus in Hospitalizedpediatric Patients with Acute Respiratory Illness: A Cross-Sectional Study in Southern China, from 2013 to 2016. BMJ Open, 8, e019308. https://doi.org/10.1136/bmjopen-2017-019308
