Sperm DNA Links from Sperm to Ovum to Implant Genetic Changeability: an Overview

Sperm DNA disintegration is known to cooperate male fertility. The data bring about that sperm DNA cleavage can be competently treated with orally administered antioxidant during a relatively short moment period. It is an accepting thought that the two types of DNA become visible to be distinctive and autonomously packaged molecules; though, investigation has established the symbiotic nature of these structures in contributing to male infertility. Data should continue to be gathered to ascertain strong correlation between conventional semen examination parameters and sperm DNA integrity; this information remains contentious and inadequate in clinical practice until certain novel techniques for the diagnosis and treatment of sperm DNA can be established. Rather more modern technology should be employed to associate such information into practical clinical awareness. This overview compiles certain specific reports pertaining to studies on sperm DNA physiology, biochemistry and molecular biology to provide further new insights into establishing hypothesis that sperm DNA integrity is both enormously fragile and remarkably significant for male fertility. Keywords: Apoptosis; Male infertility; Sperm DN