Idiopathic Pulmonary Vein Thrombosis – A presentation of two case reports and review of the current literature

Pulmonary vein thrombosis (PVT) is a rare condition that has been associated with lobectomy and lung transplants. With increasing imaging technology, we are increasingly faced with the diagnosis and difficult treatment decisions for pulmonary vein thrombosis. Currently the clinical significance and treatment options are limited. Currently to our knowledge, only around ten individual cases of pulmonary vein thrombosis have been described. We review the cases and summarize demographics, comorbidities, clinical presentations, method of diagnosis, workup, treatment, and follow up. We also share our two cases and experiences with this condition. With the increased utilization of imaging, clinicians will identify PVT more frequently. Treatment should be considered if signs of dyspnea, hypoxia, and chest pain are present. Workup for thrombophilia should considered based on clinical history of thrombosis and the discretion of the clinician. Keywords: Thrombosis; Pulmonary vein; Pulmonary hypertension; Anticoagulatio