The Determinants Of Mean Central Venous Pressure For Shock Patients

Objectives: The determinant of mean central venous pressure (MCVP) has been derived in the report with 113 shock patients containing 20 characters. Background: The determinants of MCVP for shock patients has not been derived explicitly. Material & methods: The current study has included113 shock patients containing 20 characters. The data site is: http://www. umass.edu/statdata/statdata/data/shock.txt Statistical analysis has been done by joint generalized linear models (JGLMs). Results: From the mean model of MCVP, it is found that MCVP is positively associated with survival status (SURVIVE) (P=0.0009), mean arterial pressure (MAP) (P< 0.0001), body surface index (BSI) (P=0.0001), mean circulation time (MCT) (P< 0.0001), plasma volume index (PVI) (P=0.0333), while it is negatively associated with diastolic blood pressure (DBP) (P< 0.0001), appearance time (AP) (P=0.0016), urinary output (UO) (P=0.0120). Variance of MCVP is negatively associated with BSI (P=0.0024), MCT (P=0.0236), red cell index (RCI) (P=0.0183), and it is positively associated with UO (P=0.0316), PVI (P=0.1228), hemoglobin (HG) (P=0.0008). Conclusion: The report concludes that MCVP increases as MAP, or BSI, or MCT, or PVI increases, or DBP, or AP, or UO decreases. These information is a new addition in medical literature. Keywords: Blood biochemical parameters; Cardiac index; Mean arterial pressure; Mean central venous pressure; Plasma volume index; Joint generalized linear models (JGLMs