Molecular Machines: I. An Overview of Biological and Synthetic Angstromic Devices

A molecular machine is a group of molecular components that are able to produce quasi-mechanical movements when exposed to specific stimuli. There are three broad divisions of the molecular machines, namely natural or biological, synthetic, and natural-synthetic hybrid machines. Biological motors convert chemical energy to produce linear or rotary motion as well as controlling many biological functions. Examples of the linear motions are proteins, muscle contraction, intracellular transport, signal transduction, ATP synthase, membrane translocation proteins and the flagella motor. The rotary motor example of biological molecular machines is the synthesis and hydrolysis of ATP. Synthetic molecular machine includes motors, propellers, switches, shuttles, tweezers, sensors, logic gates. Natural-synthetic hybrid systems are mechanical motor such as those inspired from DNA-based structures