Clearance of BK Virus Nephropathy by Combination Antiviral Therapy With Intravenous Immunoglobulin

Reactivation of BK polyoma virus causes a destructive virus allograft nephropathy (BKVAN) with graft loss in 46%. Treatment options are limited to reduced immunosuppression and largely ineffective antiviral agents. Some studies suggest benefit from intravenous immunoglobulin (IVIG)