Antigen delivery format variation and formulation stability through use of a hybrid vector

DOI: 10.1016/j.jvacx.2019.100012

Keywords: Vaccine delivery, DNA vaccine, Pneumococcal disease, Streptococcus pneumoniae, Pneumococcal surface protein A (PspA) PspA, pneumococcal surface protein A, APCs, antigen presenting cells, CPSs, capsular polysaccharides, PCVs, pneumococcal conjugate vaccines, NVT, non-vaccine type, PhtD, histidine triad protein D, PcpA, pneumococcal choline-binding protein A, CFA, Complete Freund's Adjuvant, LBVs, live bacterial vectors, PAMPs, pathogen-associated molecular patterns, PHV, periplasmic hybrid vector, CHV, cytoplasmic hybrid vector, SHV, surface hybrid vector, ClyA, cytolysin A, pHV, plasmid hybrid vector, LLO, listeriolysin O, CDM, chemically defined bacterial growth medium, SC, subcutaneous, IP, intraperitoneal, IN, intranasal, EHV, empty hybrid vector, AS, aqueous storage, DS, desiccated storage

Full-Text   Cite this paper   Add to My Lib

Abstract:

Full-Text