Beneficial Effects of Adalimumab Counteracted in Patient with Common Variable Immunodeficiency Disorder (CVID) Receiving IVIG: Case Report

Adalimumab is a monoclonal antibody (mAb) against TNF alpha used to treat rheumatoid arthritis (RA). Despite prevalence of autoimmune disease in CVID, there are no published cases of negative interactions between IVIG and adalimumab.