Specific IgE to gelatin as a cause of anaphylaxis to zoster vaccine

Reading the recent letter from Stone et？al1 reminded us of a subject from our previous galactose-α-1,3-galactose (alpha-gal) study. Indeed, she may well be the same 76-year-old lady found in the letter (Table E1) who was reported as negative to alpha-gal. Her first reaction to meat started 45？minutes after eating barbecue, only a few months following her recovery from Lyme disease.2,3 Since then she has had multiple reactions of varying severity, some of which started less than 1？hour after ingestion of red meat.