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Theranostics  2018 

Pharmacological Ascorbate Suppresses Growth of Gastric Cancer Cells with GLUT1 Overexpression and Enhances the Efficacy of Oxaliplatin Through Redox Modulation

DOI: 10.7150/thno.21745

Keywords: pharmacological ascorbate, gastric cancer, chemotherapy, reactive oxygen species, GLUT1

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Abstract:

Rationale: The antitumor activity of high-dose ascorbate has been re-evaluated recently, but the mechanism underlying cell-specific sensitivity to ascorbate has not yet been clarified.

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