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Theranostics 2018
Long Non-coding MIR205HG Depletes Hsa-miR-590-3p Leading to Unrestrained Proliferation in Head and Neck Squamous Cell CarcinomaDOI: 10.7150/thno.22167 Keywords: gene-expression/non-coding RNA/proliferation/HNSCC/mutant p53/YAP Abstract: Over 70% of head & neck squamous cell carcinoma (HNSCC) patients carry TP53 oncogenic mutations. Here we studied the role of specific tumor-derived mutant p53 proteins in the aberrant transcription of long non-coding (lnc) MIR205HG gene in head and neck cancer cells.
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