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Theranostics  2018 

Prostaglandin E2 hydrogel improves cutaneous wound healing via M2 macrophages polarization

DOI: 10.7150/thno.27385

Keywords: prostaglandin E2 (PGE2), macrophages, molecular imaging, hydrogel, wound healing, angiogenesis

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Abstract:

Wound healing is regulated by a complex series of events and overlapping phases. A delicate balance of cytokines and mediators in tissue repair is required for optimal therapy in clinical applications. Molecular imaging technologies, with their versatility in monitoring cellular and molecular events in living organisms, offer tangible options to better guide tissue repair by regulating the balance of cytokines and mediators at injured sites.

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