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P21-activated kinase 7 (PAK7) interacts with and activates Wnt/β-catenin signaling pathway in breast cancer

DOI: 10.7150/jca.24934

Keywords: P21-activated kinase 7, Wnt/β-catenin signaling pathway, cell proliferation, cell migration, breast cancer

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Abstract:

Background: Breast cancer is the highest incidence of tumor in women, which seriously threaten women's health. The occurrence and progression of breast cancer is linked to inactivation or downregulation of tumor suppressors, and activation or upregulation of oncogenes. However, the mechanism of PAK7 involving in the occurrence and progression of breast cancer is not yet fully understood.

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