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DOI: 10.3971/j.issn.1000-8578.2019.18.1602
Keywords: A Scientometric Analysis,A Case Report of Four Primary Malignant Tumors,Advances in Role of Cyclooxygenase 2 in Development and Progression of Cancer,Dedifferentiated Liposarcoma of Testis: A Case Report and Literature Review,Diffusion-weighted Magnetic Resonance Imaging Evaluates Salivary Gland Function Damage in Nasopharyngeal Carcinoma Patients Treated with Intensity-modulated Radiation Therapy,Research Advances on Effect of Adipose-derived Stem Cells on Biological Characteristics of Breast Cancer,Advances of 125I Radioactive Particle Chain Intracavitary Brachytherapy,Expression of Infiltrating NK Cell Surface Receptors in Peripheral Blood and Cancer Tissues of Patients with Esophageal Squamous Cell Carcinoma,Risk Factors of Pathological Upstaging for Patients with Clinical T2N0M0 Esophageal Squamous Cell Carcinoma,Progress of Stimulation Response Strategy Based on Nanomaterials in Tumor Therapy,Advances in Molecular Mechanisms of Early Bone Metastasis,Diagnostic Value of Peripheral Blood NLR and PLR in Gastrointestinal Pancreatic Neuroendocrine Neoplasm,Advances of Ribonucleotide Reductase Inhibitors on Cancer
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摘要 G蛋白偶联受体激酶（G protein-coupled receptor kinases, GRKs）通过特异性地磷酸化活化状态的G蛋白偶联受体（G protein-coupled receptors, GPCRs）终止GPCR信号转导、以及磷酸化非GPCR等参与广泛细胞生理和病理活动。近些年有关GRKs与肿瘤发生和演进的关系研究取得了长足进展，但详细的分子机制有待进一步揭示。本文讨论非视紫质GRKs对多种肿瘤细胞的不同调控作用，以期为深入开展该领域研究提供新思路
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