18F-FDG PET/CT代谢参数与结直肠癌临床病理特征的关系
DOI: 10.3971/j.issn.1000-8578.2019.19.0665
Keywords: A Meta-analysis,Prognostic and Clinicopathological Significance of PD-L1 Expression for Colorectal Cancer: A Meta-analysis,Composition and Laboratory Examination Characteristics of 187 Colorectal Cancer Patients with Schistosomiasis,Clinical Effect of Oral Nutritional Supplements in Patients with Colorectal Cancer After Emergency Surgery,Effects of NDUFA4 Overexpression on Growth of Human Colon Cancer Cells in vitro,Progress of Inhibiting Embden-Meyerhof-Parnas in Treatment of Colorectal Cancer,Influence of TYMP Polymorphism on Clinical Outcomes of Colorectal Cancer Patients Received Adjuvant Chemotherapy After R0 Resection,Established of Serum Diagnostic Model for Colorectal Cancer Patients Using MB-WCX and MALDI-TOF MS,Mechanism of Bacterial Biofilm Involved in Colorectal Carcinogenesis,Expression and Correlation of Id-1, MMP-9 and LMVD in Colorectal Adenocarcinoma Tissues,Mortality Trend of Colorectal Cancer in Kunshan City, Jiangsu Province, 1981-2014,Recent Advances of Correlation of Mismatch Repair System hMutS, hMutL Variation and Colorectal Cancer,Application of 18F-FDG PET/CT in Follow-up of Primary Breast Cancer Patients with Increased Serum CEA and(or) CA153,Research Progress of Association of Vitamin D3 and Colorectal Cancer,LncRNA Colorectal Neoplasia Differentially Expressed(CRNDE) Regulated Cell Proliferation and Migration in Glioma
Abstract:
摘要 目的 探讨18F-FDG PET/CT代谢参数与结直肠癌临床病理特征的关系。方法 纳入358例CRC患者行治疗前18F-FDG PET/CT显像，测量CRC原发灶最大标准摄取值、平均标准摄取值、肿瘤代谢体积和病灶糖酵解总量，分析其与原发灶位置、病理特征及TNM分期的关系。结果 结肠癌原发灶MTV及TLG值最高，乙状结肠癌次之，直肠癌最低，组间差异有统计学意义（P<0.001）。低/中低分化直肠癌SUVmax值高于中/高分化直肠癌（P=0.028）。黏液腺癌原发灶MTV值较普通型腺癌大（P=0.023）。T4期原发灶MTV和TLG值高于T2/3期病灶（P=0.0001, P=0.007）。存在远处转移的乙状结肠癌原发灶SUVmax及SUVmean低于无远处转移者（P=0.015, P=0.011）。结论 CRC原发灶代谢参数与位置、病理特征及TNM分期相关，能部分反映肿瘤病理特征，揭示CRC异质性
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