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-  2019 

肠道菌群紊乱与肝癌的研究进展

DOI: 10.3971/j.issn.1000-8578.2019.19.0462

Keywords: A Case Report,Knockdown of EN2 Induces Apoptosis and Enhances PTEN Protein Expression in Hepatocellular Carcinoma Cells,Comparison of Survival Rates Based on Recommended Treatment Algorithms of BCLC or HKLC Staging Systems for Hepatocellar Carcinoma Patients,Ampelopsis Regulates Invasive Activity and Invasion Gene Expression of Hepatocellular Carcinoma HepG2 Cell Line Through Dermcidin Protein,TEC Expresses Highly in Hepatocellular Carcinoma and Is Involved in Drug Resistance,3E10 Targeting CD24 Enhances Chemotherapy Sensitivity of Hepatocellular Carcinoma HuH-7 Cells,Prognosis of Stage ⅡB-Ⅲ Thoracic Esophageal Carcinoma Patients Treated with Prophylactic After Radical Esophagectomy,Prophylactic Radiotherapy for Procedure Tract Metastases in Malignant Pleural Mesothelioma: A Meta-analysis,Comparison of Efficiency and Safety Between Radiofrequency Ablation and Stereotactic Body Radiotherapy on Primary Small Hepatocellular Carcinoma,Effect of MicroRNA-340 on Proliferation and Apoptosis of Hepatocellular Carcinoma Cell Lines,Effect of Cyclin G1 on Radiosensitivity of Hepatocellular Carcinoma HepG2 Cells and Its Mechanism

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Abstract:

摘要 肝细胞肝癌(HCC)是常见的消化系统恶性肿瘤,HCC的发生涉及多种因素,如环境、代谢与基因等。近期研究发现,肠道菌群失调与HCC的发生发展有着密切联系,其可能的机制包括菌群移位与内毒素血症引起肝细胞的慢性炎性反应以及肠道菌群代谢产物如短链脂肪酸、胆汁酸等对HCC的诱导等。目前多种改善肠道菌群紊乱的方法在HCC的治疗中显示出较为光明的前景。本文将对肠道菌群引起HCC的多种机制以及针对肠道菌群失调的HCC预防与治疗措施进行综述

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