菌群的生物节律现象及其临床意义
Biorhythmic phenomenon of microflora and its clinical significance

生物节律现象广泛存在于各类生物体内，而菌群生物节律与宿主生物节律的关系是近年研究的热点 之一，研究层面从生态系统到分子机制一应俱全，并在多国开展了基于菌群— 宿主生物节律互作的临床试验研 究，相关成果对开发时间特异性疗法及微生物制剂具有重要意义。
Biological rhythm phenomenon widely exists in various organisms. The relationship between bacteria and host circadian biological rhythm is one of hot research subjects in recent years. The researches of different levels from molecular mechanism to ecological system are all available. The clinical trials of bacteria-host interaction based on biological rhythm have been carried out in many countries. The relevant achievements of those researches have great implications for the development of time-specific therapy and microbial preparations