基于传输线模型的人体脉搏波仿真分析
Human pulse wave simulation analysis based on transmission line model

利用55段人体动脉树建立传输线模型，数值仿真人体动脉树中脉搏波的传播，在心脏输出体积流率波一定的条件下，改变模型分支外周阻力来探讨阻力变化对脉搏波的影响规律。研究表明：随着某分支外周阻力的增加其自身的血流量迅速下降，不同器官的阻力比增加均能引起主动脉和桡动脉平均血压的升高，且升高的趋势逐渐减小；当阻力比η=4时，肝、脾、胃、上肠膜、右肾、下肠膜分支桡动脉平均血压较正常分别增加2.86%、4.55%、1.90%、12.15%、9.81%、1.49%。脉搏波谐波与各器官病变之间存在客观联系是中医脉诊的依据，而通过对桡动脉脉搏波频域分析发现，脉搏波谐波振幅与各器官外周阻力变化的联系不明显，仿真时还需考虑不同器官病变时心脏自我调节作用的影响。
A transmission line model was established by using 55 human arterial trees to simulate the propagation of pulse wave in human arterial tree, and the effect of resistance change was investigated by changing the peripheral resistance of the model branch under the condition of the settled volume flow rate wave of cardiac output. The results show that with the increase of the peripheral resistance of a branch, its blood flow rate drops rapidly, the rise of the average blood pressure of the aorta and radial artery can be caused by the increase of the resistance ratio of different organs, and the trend of the elevation decreases gradually. When η is set as 4, the radial artery mean pressure is 2.86%,4.55%,1.90%,12.15%,9.81% and 1.49% higher than normal respectively with the flow resistance increase of liver, spleen, stomach, superior mesenteric, right kidney and inferior mesenteric branch. The objective relationship between pulse wave harmonics and the pathological changes of the organs is the basis of pulse diagnosis in traditional Chinese medicine. By analyzing the pulse wave frequency domain of radial artery, it is found that the connection between the amplitude of pulse wave and the change of peripheral resistance of each organ is not obvious. And the effect of cardiac self-regulation with different organ lesions should be considered in the simulation