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复苏延迟体(regrowth-delay body)作为一种标示休眠细菌的可逆亚细胞结构

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Abstract:

大约在1895年前后,人们就注意到一个有趣的现象,那就是在实验室批量培养细菌(如伤寒杆菌)的时候,每当细胞进入快速生长分裂状态之前,总是存在一个无任何生长迹象的潜伏期(latent period)或延迟期(lag phase)。而且这种复苏过程的延迟时间的长短与细胞经历上一次培养过程的时间有关:培养时间越长(细胞越老),复苏的延迟期越长;培养时间越短(细胞越年轻),复苏的延迟期越短[1]。究其原因,当时的观点是经历了长时间培养的细菌细胞受到了损伤,所以再次生长时需恢复一段时间[1]。.....

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