The Follicular Benignancy- Desmoplastic Trichoepithelioma - The Follicular Benignancy- Desmoplastic Trichoepithelioma - Open Access Pub

Trichoepithelioma is a benign, cutaneous neoplasm originating from the hair follicle and is categorized into singular trichoepithelioma, multiple trichoepithelioma and desmoplastic trichoepithelioma wherein desmoplastic trichoepithelioma is cogitated as an exceptional, cutaneous adnexal tumour. Desmoplastic trichoepithelioma was initially scripted by Hartzell in 1904 wherein the lesion was described as a benign, cystic epithelioma. Desmoplastic trichoepithelioma can be additionally nomenclated as epithelioma adenoides cysticum, morphea - like epithelioma or sclerosing epithelial hamartoma 1. Familial instances of desmoplastic trichoepithelioma are infrequent and can be misdiagnosed on account of adjunctive benign, cutaneous, adnexal neoplasms depicting subtle clinical features, excepting a nodular basal cell carcinoma. Cogent clinical and histological features can assist the diagnosis of desmoplastic trichoepithelioma 1, 2. DOI10.14302/issn.2689-5773.jcdp-20-3218 Trichoepithelioma is a benign, cutaneous neoplasm originating from the hair follicle and is categorized into singular trichoepithelioma, multiple trichoepithelioma and desmoplastic trichoepithelioma wherein desmoplastic trichoepithelioma is cogitated as an exceptional, cutaneous adnexal tumour. Desmoplastic trichoepithelioma was initially scripted by Hartzell in 1904 wherein the lesion was described as a benign, cystic epithelioma. Desmoplastic trichoepithelioma can be additionally nomenclated as epithelioma adenoides cysticum, morphea - like epithelioma or sclerosing epithelial hamartoma 1. Familial instances of desmoplastic trichoepithelioma are infrequent and can be misdiagnosed on account of adjunctive benign, cutaneous, adnexal neoplasms depicting subtle clinical features, excepting a nodular basal cell carcinoma. Cogent clinical and histological features can assist the diagnosis of desmoplastic trichoepithelioma 1, 2. Disease Characteristics Desmoplastic trichoepithelioma is an exceptional, benign adnexal tumefaction arising from basal cells of outer root sheath of the hair follicles. With an estimated incidence of 1 : 5000, desmoplastic trichoepithelioma commonly appears in young and middle aged women, demonstrates a female preponderance and usually appears within 8 years to 81 years 1, 2. Multiple foci of preliminary lesions of desmoplastic trichoepithelioma can concur with foci of basal cell carcinoma, thus indicating a concomitant genetic predisposition. As a tumefaction delineating an autosomal dominant mode of disease inheritance, desmoplastic trichoepithelioma can be associated