对待残存G0期瘤细胞只有让其进入复制期后再杀伤这一种策略吗？
Is chemotherapy the only option to treat the residual solid tumor cells at the G0 phase after inducing them into the cell cycle?

对于生长分数低、对化疗不够敏感的实体瘤，当前不少教材在介绍其临床治疗策略时，大都表述 为：先用放射或手术治疗将肿瘤缩小或去除，让残存的瘤细胞从G0期进入复制期后再应用化疗。在将肿瘤缩小或 去除之后，以上表述只提到采用化疗杀伤从G0期进入复制期的瘤细胞的杀伤性策略，忽略了将残存瘤细胞逆转成 正常细胞或将其稳定在G0期休眠等非杀伤性策略，可能会让读者误以为杀伤残存瘤细胞是惟一的选择。鉴于教材 的权威性以及建立读者“消灭与改造并举”的综合性抗癌思维的重要性，笔者建议对类似描述进行补充或修改。
When referring to the clinical treatment strategies for the solid tumors that have low growth fraction and are not sensitive enough to chemotherapy, most current textbooks describe as follows: firstly, use radiation or surgical treatment to shrink or remove tumors, then apply chemotherapy after the transition of the residual cancer cells from phase G0 into the cell cycle. To treat the residual cancer cells, the description the above only involves the elimination strategy of using chemotherapy, but it ignores noncytocidal strategies that reversing the residual cancer cells into normal cells or stabilizing them at G0 phase, etc. That may induce the readers mistakenly to believe that eliminating the residual cancer cells is the only option. In consideration of the textbooks’ authoritativeness and the importance of establishing a comprehensive anticancer thinking for the readers, we suggest that such a description should be supplemented or modified