Editorial Perspective on Application of Physics in Molecular Biology

The Physics in molecular biology plays a pivotal role in the quantitative determination of many aspects. Of course, it is not directly appeared in living organisms but the development of physical statistical tools are increasing the importance of quantitative analysis of complex biomolecules during the process such as energy transduction of metabolic pathways, DNA & RNA division and replications, Protein folding and stabilization, Enzyme-Ligand interactions, Ionization of chemical substances, allosteric regulatory pathways, identification and quantitative measurement of molecules, etc. In this paper, brief applications are showed which were applied physically in the biomolecules. Keywords: Physics; applications; Molecular biology; Molecular biology studies the biological activity between biomolecules in the various systems of a cell in living organisms, including the interactions between DNA, RNA, proteins, lipids and carbohydrates and their biosynthesis, as well as the regulation of these interactions. Living organism must perform work to survive themselves as long as possible. The reactions that occur in the cell may require the energy to process such reactions. In the evolution, the cells develop the mechanisms for coupling of energy during the photosynthesis, molecular metabolism, enzyme kinetics and ecosystem balancing by prokaryotes, etc. These are the reactions which emphasize the energy transduction. For quantitative measurement of energy transduction in mechanisms, the developed physical statistical tools are helpful to increase the efficacy of measurements. The reason behind that the living organism to carry the reactions is to exist the dynamic steady state level that is far from the equilibrium. A living organism is an open system and it exchange both energy and matter with its surroundings. For this determination, 3 laws of thermodynamics help to predict the energy transduction in the system. Chemical, electromagnetical, mechanical and osmotical energy transduction was predicted by first law with great efficacy. In second law of thermodynamics, mainly Gibb’s free energy determines the enthalpy and entropy changes during the chemical reaction. It state’