Morphometric Assessment of Aging Impact in Cranial/Ventricles’ Volumes and CT/MRI Imaging Systems Parameters

A retrospective study aims to assess aging impact in cranial/ventricles volumes and the effect in signal intensity of imaging modalities (CT & MRI). The analysis of collected data using Excel and SPSS showed that: aging has less significant (R2 =0.4) impact on ventricle volume generally and the correlation best fitted to equation: Volume = 1.46 age - 40.742. The impact of aging in ventricles volume was significant (p = 0.05) increment after 69 years with prominent effect among male relative to female; and steady before the age of 69 years old. Aging had less significant decreasing impact (R2 = 0.3) in signal intensity (T1, T2) of white and gray matter and having prominent high signal intensity of white mater relative to gray mater. The age showed high significant (R2 = 0.8) reducing impact in white matter HU that fitted to equations of the following forms: HU = 0.53 age + 9.6864; while there is an increasing impact in gray matter HU that fitted to: HU = -0.26 age + 40.093