Effective Tidal Volume for Normocapnia in Very-Low-Birth-Weight Infants Using High-Frequency Oscillatory Ventilation

Removal of CO2 is much efficient during high-frequency oscillatory ventilation (HFOV) for preterm infants. However, an optimal carbon dioxide diffusion coefficient (DCO2) and tidal volume (VT) have not yet been established due to much individual variance. This study aimed to analyze DCO2 values, VT, and minute volume in very-low-birth-weight (VLBW) infants using HFOV and correlates with plasma CO2 (pCO2)